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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PTPN14
All Species:
26.97
Human Site:
T497
Identified Species:
59.33
UniProt:
Q15678
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q15678
NP_005392.2
1187
135261
T497
M
R
E
R
H
P
Y
T
V
P
Y
G
P
Q
G
Chimpanzee
Pan troglodytes
XP_001171329
1187
135241
T497
M
R
E
R
H
P
Y
T
V
P
Y
G
P
Q
G
Rhesus Macaque
Macaca mulatta
XP_001106167
1187
135194
T497
M
R
E
R
H
P
Y
T
V
P
Y
G
P
Q
G
Dog
Lupus familis
XP_849236
1187
134903
T497
M
R
E
R
H
P
Y
T
V
P
Y
G
P
Q
G
Cat
Felis silvestris
Mouse
Mus musculus
Q62130
1189
135012
T497
M
R
E
R
H
P
Y
T
V
P
Y
A
H
Q
G
Rat
Rattus norvegicus
Q62728
1175
133393
A503
I
R
E
H
P
H
L
A
S
P
Q
S
A
H
Y
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511302
1193
135259
T502
M
R
E
R
H
P
Y
T
V
P
Y
G
L
Q
A
Chicken
Gallus gallus
XP_419419
1191
135566
T502
I
R
E
R
H
P
Y
T
V
T
Y
G
P
Q
G
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001339962
834
94004
G192
T
E
R
R
P
V
V
G
A
V
S
V
P
E
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P28191
1026
115075
N384
I
D
S
S
R
Y
T
N
T
T
T
T
D
S
P
Sea Urchin
Strong. purpuratus
XP_796215
1318
147575
S508
L
L
T
V
S
E
Q
S
Q
S
V
G
N
L
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
98.9
95.6
N.A.
91.5
53.7
N.A.
87.9
84.9
N.A.
32.8
N.A.
N.A.
N.A.
24.7
34.5
Protein Similarity:
100
99.7
99.5
97.2
N.A.
95.6
70.7
N.A.
92.1
91.5
N.A.
48.1
N.A.
N.A.
N.A.
42
51.7
P-Site Identity:
100
100
100
100
N.A.
86.6
20
N.A.
86.6
86.6
N.A.
13.3
N.A.
N.A.
N.A.
0
13.3
P-Site Similarity:
100
100
100
100
N.A.
86.6
26.6
N.A.
86.6
93.3
N.A.
20
N.A.
N.A.
N.A.
6.6
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
10
10
0
0
10
10
0
10
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
10
0
0
0
0
0
0
0
0
0
0
10
0
0
% D
% Glu:
0
10
73
0
0
10
0
0
0
0
0
0
0
10
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
10
0
0
0
64
0
0
64
% G
% His:
0
0
0
10
64
10
0
0
0
0
0
0
10
10
0
% H
% Ile:
28
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
10
10
0
0
0
0
10
0
0
0
0
0
10
10
10
% L
% Met:
55
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
10
0
0
0
0
10
0
0
% N
% Pro:
0
0
0
0
19
64
0
0
0
64
0
0
55
0
10
% P
% Gln:
0
0
0
0
0
0
10
0
10
0
10
0
0
64
0
% Q
% Arg:
0
73
10
73
10
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
10
10
10
0
0
10
10
10
10
10
0
10
0
% S
% Thr:
10
0
10
0
0
0
10
64
10
19
10
10
0
0
0
% T
% Val:
0
0
0
10
0
10
10
0
64
10
10
10
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
10
64
0
0
0
64
0
0
0
10
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _